Actini in North America

Thermal process expertise, closer to North American customers

For more than 70 years, ACTINI has designed, manufactured and commissioned thermal treatment systems for pharmaceutical, biotechnology, research and bioproduction applications. Today, ACTINI USA brings this thermal process engineering expertise closer to customers across North America.

Our North American organization combines local project support with ACTINI’s global engineering and manufacturing experience in effluent decontamination, liquid sterilization and pH neutralization systems for critical process applications.

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Explore our process solutions

Decontamination

Thermal Effluent Decontamination Systems (EDS) for laboratories, biotech, pharmaceutical manufacturing and high-containment facilities.

Sterilization

Continuous thermal treatment systems for culture media, fermentation broth, active ingredients and other process liquids.

Neutralization

Automated batch and continuous pH neutralization systems for decontaminated effluent and process wastewater.

Micro decontamination unit

Sterilization

Decontamination

Neutralization

Services sur site - électricité

Thermal process expertise for North American projects

ACTINI supports critical liquid-process applications across pharmaceutical manufacturing, biotechnology, research and bioproduction.

Our expertise includes:

  • Thermal Effluent Decontamination Systems (EDS)
  • Batch and continuous biowaste treatment
  • Liquid sterilization and HTST processing
  • pH neutralization and process wastewater treatment
  • High-containment applications
  • Process engineering and equipment integration
  • Automation and instrumentation
  • FAT, SAT and qualification support
  • Lifecycle services and equipment upgrades

For effluent decontamination, ACTINI’s product portfolio includes standard, pre-engineered and customized systems for applications ranging from compact laboratory installations to BSL-4 facilities.

Decades of experience.
A stronger local presence.

ACTINI has supported customers in North America for many years through thermal-process equipment, engineering and project services.

Today, ACTINI USA strengthens this presence with a dedicated U.S. organization focused on closer customer support, local responsiveness and long-term equipment service.

This development is an extension of ACTINI’s existing experience in the region rather than a new starting point. It builds on established projects, customer relationships and decades of process expertise.

ACTINI USA combines this global background with strong experience in North American project expectations, including U.S. electrical requirements, pressure-equipment standards, pharmaceutical documentation, automation and qualification needs.

Our objective is straightforward: remain close to the customer from early project definition through commissioning, qualification and long-term operation.

A North American team backed by global expertise

Local support, global engineering resources

Complex pharmaceutical and biotech projects often require both local responsiveness and access to specialized process engineering resources. ACTINI USA connects North American customers and engineering companies with ACTINI’s broader process, mechanical, automation, manufacturing and service capabilities.

Our teams can support:

  • Early process definition
  • Equipment sizing and technology selection
  • System specifications and project engineering
  • Process Flow Diagrams and system layouts
  • Utility and integration requirements
  • Manufacturing and assembly
  • Automation and documentation
  • Factory Acceptance Testing (FAT)
  • Installation and commissioning
  • Site Acceptance Testing (SAT)
  • Qualification support
  • Operator training
  • Preventive maintenance and troubleshooting
  • Spare parts and retrofit

What sets our approach apart

Engineering before equipment

We believe system selection should start with the process, not with a model number. Understanding flow, product or effluent characteristics, utilities, site constraints and validation requirements comes first.

The right level of customization

ACTINI works with standardized, pre-engineered and custom-engineered platforms. The objective is to apply customization where it creates technical value, while avoiding unnecessary project complexity.

Support beyond commissioning

Our role continues after startup through training, preventive maintenance, troubleshooting, spare parts, audits and equipment upgrades.

Quality Assurance & Compliance Standards

Supporting pharmaceutical, biotech
and research facilities

Pharmaceutical manufacturing

Large pharmaceutical projects often require systems aligned with corporate standards for components, automation, instrumentation, documentation, utilities and qualification. ACTINI works with end users and engineering partners to integrate these requirements into the process design.

Biotech & bioproduction

Biotech facilities may need to scale from development and pilot operations to commercial production. ACTINI designs systems around changing capacities, process conditions, utilities and facility constraints.

CDMOs

CDMOs need systems that can support current production while remaining flexible for future products and capacities. ACTINI combines proven platforms with configurable process parameters, automation and expansion options to help balance flexibility, project cost and future requirements.

Laboratories & research facilities

For laboratories and smaller facilities, ACTINI offers compact and standardized systems designed for simplified installation, automated operation and reliable treatment.

Proven experience in critical applications

ACTINI systems are used in vaccine manufacturing, biotech facilities, research centers and laboratories around the world. More than 600 ACTINI systems are currently operating across these applications.

For effluent decontamination, ACTINI offers configurations ranging from compact batch units to high-capacity continuous systems for BSL-1 through BSL-4 facilities.

Services on site - maintenance

Engineering with the customer, not just for the customer

Our approach is built around close collaboration with customers and engineering partners. We aim to understand the process first, select proven technology where possible, engineer around genuine project requirements and remain involved through implementation and operation.

For ACTINI, a successful project is not simply equipment delivered on time. It is a system that integrates into the facility, performs as intended, can be qualified and supported, and remains reliable throughout its operating life.

ACTINI by the numbers

70+

Years of thermal process experience

600+

Systems in pharma, biotech, research & laboratory applications worldwide

3

Core process areas: decontamination, sterilization & neutralization

1

Dedicated North American team

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Let’s talk about your project

Planning a new facility, upgrading an existing process or evaluating treatment options?
Our U.S. team can help you define the right approach and connect you with ACTINI’s engineering resources.

Frequently Asked Questions

What is ACTINI USA?

ACTINI USA is ACTINI’s North American organization, supporting customers across the United States with project engineering, commissioning, qualification support and lifecycle services.

Where is ACTINI USA located?

ACTINI USA is based in Lewis Run, Pennsylvania, providing a direct point of contact for North American customers and engineering partners.

How long has ACTINI been active in thermal process engineering?

ACTINI has more than 70 years of experience designing, manufacturing and commissioning thermal treatment systems for demanding process applications.

What industries does ACTINI support in North America?

ACTINI supports pharmaceutical manufacturers, biotech and bioproduction facilities, CDMOs, research centers and laboratories requiring decontamination, sterilization or neutralization systems.

What technologies does ACTINI specialize in?

ACTINI specializes in three core process areas: effluent decontamination, continuous liquid sterilization and pH neutralization, with both standardized and engineered system configurations.

Does ACTINI provide local project support in the United States?

Yes. ACTINI USA supports North American projects from early process discussions through installation, commissioning, qualification and long-term equipment support.

Can ACTINI support custom pharmaceutical project requirements?

Yes. ACTINI can adapt systems to project-specific requirements including components, automation, instrumentation, documentation, utilities, site integration and validation needs.

Does ACTINI provide support after commissioning?

Yes. ACTINI provides training, preventive maintenance, troubleshooting, spare parts, audits and retrofit support to help customers operate and evolve their systems over time.